They include DNA restriction endonucleases (restriction enzymes) and their companion modification methylase restriction enzymes, DNA methyltransferases and related proteins, which are generally ...

Scientists have discovered that bacteria employ a type of DNA modification never before seen in nature. For several decades, researchers have known that it is possible to modify synthetic ...

Here we studied the single polypeptide Type ISP restriction-modification (RM) enzymes, which cleave random DNA between distant target sites when two enzymes collide after convergent ATP-driven ...

Through a mechanism called epigenetics, the instructions in DNA can be edited without changing the underlying code. Chemical modification is one way this can be done. For example, enzymes like ...

Emory geneticists have been studying methylation of the DNA letter A (adenine). It appears more in the mouse brain under conditions of stress, and may have a role in neuropsychiatric disorders.

A research group led by the University of Osaka has discovered that the DNA repair enzyme Polβ plays a crucial role in ...