Mitochondria are central hubs for cellular stress adaptation, with their function integrated with both apoptosis and autophagy pathways that determine cell fate. Alterations in mitochondrial ...

Autophagy (“self-eating”) is the process through which parts of the cell are degraded in the lysosome. Elucidation of the key genes essential for autophagy — originally identified in yeast — has led ...

A new study unravels the relationship between mitofusins (mitochondrial proteins) and autophagy. Using gene editing with CRISPR-Cas9, the team has been able to study these proteins without altering ...

Three primary types of autophagy are macro and micro-autophagy, as well as chaperone-mediated autophagy. Macro-autophagy moves the cytoplasmic component to its lysosome using a double-membrane vesicle ...

Autophagy is a vital process in which the body’s cells “clean out” any unnecessary or damaged components. It may be possible to induce autophagy, but there may be associated risks. Researchers have ...

You’ve probably spent most of your life unaware of autophagy, even though it’s a process that happens regularly in your body. The term became popular outside of biology textbooks only with the rise of ...

In a recent study published in the journal Neuron, researchers at the University of Cambridge and Newcastle University, UK, examined the relationship between autophagy, aging, and neurodegeneration.

Autophagy is a natural process that occurs as your body clears out and replaces damaged cell parts with new ones. It occurs within your body at all times. It has been linked to a long list of ...