The pathogen C. diff—the most common cause of health care-associated infectious diarrhea—can use a compound that kills the human gut's resident microbes to survive and grow, giving it a competitive ...
Iron storage "spheres" inside the bacterium C. diff—the leading cause of hospital-acquired infections—could offer new targets for antibacterial drugs to combat the pathogen. A team of Vanderbilt ...
Clostridium difficile is an unpleasant, sometimes severe, and potentially lethal infection. It is an enteric pathogen whose armory involves the production of a toxin leading to gut dysphoria and ...
New study reveals at a molecular level how fidaxomicin selectively targets C. Diff bacteria while sparing the innocent bacterial bystanders of the gut microbiome. Most antibiotics are double-edged ...
A novel vaccination approach developed by Vanderbilt Health researchers cleared the harmful gut bacterium Clostridioides difficile (C. diff) in an animal model of infection. An experimental vaccine ...