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When microarray-based comparative genomic hybridisation (array-CGH) became available, all HR-CGH-positive samples were also investigated by 1 Mb resolution array-CGH for more precise mapping.
Array-based comparative genomic hybridization (CGH) is a technique that allows genome wide screening of gains and losses in DNA copy number.
NimbleGen boasts that its array CGH workflow is an easy-to-use solution with no prior microarray experience necessary.
Detection of CNAs in AML As with MDS, early studies in AML with array CGH and SNP array showed the feasibility of interrogating AML genomes with array platforms and demonstrated their utility in ...
Comparative genomic hybridization (CHG) provides the densest coverage of probes for CNV detection, but the traditional technique using bacterial artificial chromosome arrays is time consuming and not ...
A single catalog array design, Human CGH 12x135K Whole-Genome Tiling v2.0, is available and enables genome-wide detection of copy number gains and losses down to ~100kb in size.
Array-based comparative genomic hybridization is able to unveil previously undetectable nuances.
They recommended that advanced genomic technologies, such as array CGH, be broadly deployed by cell culture banks to ensure consistency of the cells they provide to the research community.
Principals of Array CGH & SNP Arrays Array CGH uses competitive hybridization of fragmented tumor DNA and control DNA labeled with different fluorophores to a microarray platform to detect CNAs.