Cell signalling pathways are central to maintaining cellular homeostasis and regulating essential functions such as proliferation, apoptosis, and repair. In both cancer and neurodegenerative diseases, ...

The recent discovery of glycoRNAs on the cell surface upended the world of cell biology. These glycoRNAs were found to form ...

Human cells decode dynamics Wnt signals using an anti-resonant filter that suppresses intermediate-frequency inputs and is capable of redirecting developmental fate outcomes, including germ-layer ...

The structural and functional characteristics of mitochondria shape their role as signaling organelles, with far-reaching ...

Researchers identify bone-forming cells as the driver of scoliosis caused by a genetic disorder, which can be prevented ...

Research reveals that neural crest cells fine-tune key growth signals during early development, ensuring proper formation of ...

Researchers have identified a method to enhance the effectiveness of a promising cancer treatment. They found that modifying a specific gene improves the ability of immune cells to combat cancer for ...

New research co-led by Indiana University School of Medicine scientists has exposed a vulnerability in acute myeloid leukemia by identifying the blood cancer's reliance on a specific signaling pathway ...

Researchers have identified an enzyme that controls the maturation and long-term survival of tissue-resident macrophages.

New research from the University of St Andrews has discovered a crucial piece in the puzzle of how all animals with a spine—including all mammals, fish, reptiles and amphibians—evolved. In a paper ...

A new paper published today in Cell highlights how researchers have leveraged AI-based computational protein design to create a novel synthetic ligand that activates the Notch signaling pathway, a key ...