A map of DNA methylation changes in human organs could help researchers to discover more targets for anti-ageing therapies.

DNA methylation is a critical epigenetic mechanism in numerous biological processes, including gene regulation, development, ageing and the onset of various diseases such as cancer. Studies of ...

A comprehensive atlas maps DNA methylation across 39 human cell types, revealing a complex landscape of epigenetic regulation.

Table 1. Comparison of DNA methylation sequencing technologies. Whole-genome bisulfite sequencing (WGBS) remains the gold standard for comprehensive DNA methylation analysis. It provides base-pair ...

DNA methylation is a biochemical process that influences gene expression and plays a significant role in detoxification, energy production, and overall wellness. Life X DNA's testing process examines ...

DNA methylation profiles in whole blood samples from 77 patients with CN-AML in The Cancer Genome Atlas (LAML cohort) were analyzed. Individual 5’-cytosine-phosphate-guanine-3’ (CpG) sites were ...

PURPOSEPatients with stage II and III cutaneous primary melanoma vary considerably in their risk of melanoma-related death. We explore the ability of methylation profiling to distinguish primary ...

The FTO gene, known for its association with appetite regulation and metabolic efficiency, is included in all Life X DNA panels. FTO gene testing can provide information on genetic variants that may ...

A new research paper was published in Aging (Aging-US) on January 3, 2025, in Volume 17, Issue 1, titled "Characterization of DNA methylation clock algorithms applied to diverse tissue types." ...

After that your data is ready for most differential DNA methylation analysis using either single CpGs or differentially methylated regions, which can then be further annotated and interpreted for ...

PacBio enhances methylation detection in HiFi sequencing by licensing advanced methods, improving insights into DNA modifications.