The DNA copy that is made, called complementary DNA (cDNA), is then applied to the microarray. The cDNA binds to complementary base pairs in each of the spots on the array, a process known as ...

One of the hottest research tools these days within the academic, biotech, and pharma communities is DNA microarrays. The concept morphed from the now-classical Southern blotting procedure into ...

DNA Microarray Technology A DNA microarray is an ordered arrangement of equidistant microscopic DNA spots attached to a solid surface, such as a glass, plastic or silicon chip. Hybridization is ...

This procedure involves double-stranding a commercially synthesized DNA oligonucleotide array, binding a TF directly to the double-stranded DNA microarray and labeling the protein-bound microarray ...

A multidisciplinary team of pharmaceutics and computer-science researchers at the University at Buffalo, one of very few teams in the nation applying DNA microarray technology in studies of multiple ...

image: DNA microarrays can be easily interrogated with only the naked eye using a new electrostatic imaging technique developed in the laboratory of Jay Groves, a chemist with Berkeley Lab, UC ...

In this protocol, we have combined commercial procedures from Sigma-Aldrich and Agilent Technologies for the DNA amplification step and the microarray hybridization steps, respectively.

The innovative method combines a new experimental procedure and a new algorithm to identify gene activation captured by DNA microarray analysis with greater sensitivity and specificity. The work ...

These reactions also label the genes with fluorescent dyes. Finally, the researchers add the twice-amplified DNA to the second microarray chip labeled with DNA sequences of the known engineered genes.