DNA phosphorothioate modification is a distinctive epigenetic alteration in which a non‐bridging oxygen atom within the DNA sugar-phosphate backbone is replaced by sulphur. This covalent change ...

Relationships between DNA methylation and histone modification have implications for understanding normal development as well as somatic cell reprogramming and tumorigenesis.

The surprising discovery and function of a new DNA modification in insects, worms, and algae has been described in a new article by an international team of researchers.

Long-term, heritable changes in gene activity fundamentally shape our biology, trigger many of our diseases, and set the clock on how we age. Now, a team of U of U Health scientists is starting an ...

Researchers have discovered a DNA modification that enhances our ability to extinguish fear. The findings could help guide the development of new treatments for fear-related anxiety disorders ...

Modifi Bio is creating a new class of molecules, based on research conducted at Yale, that fragment in cells and induce DNA modifications, which are irreparable in cancer cells with DNA repair ...

It contains dynamic DNA modifications that carry key inheritable epigenetic information passed among generations of cells,” said He, the John T. Wilson Distinguished Service Professor in Chemistry and ...