Unexpected slowdowns or spikes in this signal were often interpreted as knots in DNA. But now, a new study published Aug. 12 ...

DNA replication likes one direction. Not the boy band, but rather it prefers to replicate in a certain direction over the other. Publishing their findings in Science Advances, scientists have ...

Life depends on double-stranded DNA unwinding and separating into single strands that can be copied for cell division. Scientists have determined at atomic resolution the structure of machinery ...

Previous attempts to examine the structure of the enzyme–DNA–nucleotide complex poised for catalysis have involved the use of unreactive DNA that lacks a hydroxyl group (OH) in its deoxyribose ...

On the DNA assembly line, two proofreading proteins work together as an emergency stop button to prevent replication errors. New research from North Carolina State University and the University of ...

Holliday junctions can be formed during genetic recombination and affect many biological processes, including DNA replication and gene regulation.

Find out how the structure of DNA was discovered by Francis Crick and James Watson, and why the discovery revolutionized science and medicine ...

DNA aptamers are powerful molecular tools in biosensing, bioimaging and therapeutics. However, a limited understanding of ...

Postmitotic myotubes cannot complete DNA replication following forced cell cycle reactivation. Comparative genomic ...

At school, it's often presented as a tidy double helix but scientists are revealing the varied and intricate shapes of DNA molecules.

A new study has found that ORC plays a broad, unexpected role in regulating human cell gene expression and chromatin ...