To use CRISPR enzymes to edit gene sequences, scientists can tailor them to target a specific sequence within the three billion DNA base pairs in the human genome.

Plant genome editing through CRISPR-Cas holds transformative potential, yet its precision remains hampered by low gene targeting (GT) efficiency. This study presents a strategy to enhance CRISPR ...

In practice, however, developing safe and effective gene therapies has not been easy. Even when identifying a disorder’s genetic basis is fairly straightforward, finding the appropriate delivery ...

Scientists have developed a tool that can precisely control gene expression without altering the underlying DNA sequence.