Forkhead box O (FOXO) genes are involved in multiple signaling pathways and play critical roles in a number of physiological and pathological processes. This review will focus on the role of these ...

In an elegant, multiple-gene knockout experiment, a team of Boston scientists has discovered that a trio of molecules, called FoxOs, are fundamentally critical in preventing some cancers, maintaining ...

Although the molecular machinery controlling aging has been well studied in lower organisms, it is unclear whether these mechanisms are conserved in mammals. A recent study supports a role for an ...

In a recent study, Indian researchers from the Department of Biochemistry, University of Delhi, reviewed a possible vital coalition of FoxOs - the Forkhead Box O subfamily of protein transcription ...