Epistasis, or interactions between genes, has long been recognized as fundamentally important to understanding the structure and function of genetic pathways and the evolutionary dynamics of ...

Experimental approaches In the past, the function of a protein of interest was first identified and then its structure determined by means of time-consuming x-ray or NMR experiments. In contrast ...

The approach using reconstructed ancestral genes has paid off. 'The amino acid sequence of ancestral proteins and contemporary proteins are 90 percent identical, while their functions are ...

Each gene, in turn, can control many aspects of a cell's function. Testing these hundreds of genes in mice using current methods would be extremely slow and expensive—near impossible, in practice." ...

The hippocampus is an important brain region known to support various cognitive (i.e., mental) processes, including the encoding and retrieval of memories, learning, decision-making and the regulation ...

Dyslexia is a common learning difficulty in which genes often play a role. How do genes associated with dyslexia relate to brain structure in the general population? In a large-scale study ...