LpxC inhibitors target a zinc-dependent deacetylase that catalyses the first committed step in lipid A biosynthesis, an essential process for the viability of Gram-negative bacteria. As lipid A forms ...

Gram-negative bacteria's thick outer membrane prevents entry of toxic molecules, including antibiotics. Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to ...

Jackson Ryan was CNET's science editor, and a multiple award-winning one at that. Earlier, he'd been a scientist, but he realized he wasn't very happy sitting at a lab bench all day. Science writing, ...

There are many ways of classifying bacteria. One method is based on the cell membrane. In 1884, a bacteriologist named Christian Gram created a test that could determine if a bacterium had a thick, ...

The emergence of multi-drug resistance bacteria and healthcare-associated infections are frequent issues in the treatment of suppurating wounds. A group of researchers has created a bactericidal ...

An international research team has demonstrated that Janus nanoparticles can disrupt the defenses of drug-resistant ...

Gram-positive bacteria show blue or purple after Gram-staining in a laboratory test. They have thick cell walls. Gram-negative bacteria show pink or red on staining and have thin walls. They release ...