Senescent fibroblasts are aging cells in connective tissue that no longer divide and protect against tumor development. Yet, these same cells can promote cancer growth in a laboratory setting. Until ...

University of Virginia School of Medicine scientists have revealed how mistakes in the final step of cell division can have ...

A new study by the Garvan Institute of Medical Research has uncovered a hidden mechanism explaining why breast cancer can ...

Being overweight or obese has long been linked to a greater risk of developing or dying from breast cancer. New research suggests a reason: Certain breast cancer tumors may feed on neighboring fat ...

Left: In normal gastric tissue, gastric epithelial cells rely on growth signals provided by the surrounding microenvironment. In particular, WNT signals — such as WNT2 secreted by neighboring cells — ...

Researchers at Moffitt Cancer Center have developed a new way to predict how cancer cells evolve by gaining and losing whole chromosomes, changes that help tumors grow, adapt and resist treatment. In ...

A feature of pancreatic cancer cells' surroundings determines whether they grow fast or become resistant to chemotherapy, a new study shows. The ability of these cancer cells to adapt quickly and ...

Cancer always seems to break the rules — defying normal biology and finding new ways to survive, grow, and spread. That ability fascinated Rushika M. Perera, PhD, when she was younger. It’s what ...

A feature of pancreatic cancer cells’ surroundings determines whether they grow fast or become resistant to chemotherapy, a new study shows. The ability of these cancer cells to adapt quickly and ...

Gastric (stomach) cancer remains one of the most common and deadly cancers in East Asia, including Korea. Yet despite its high prevalence, it has received far less molecular attention than colorectal ...

Published online Feb. 16 in the journal Cell, the new work shows that a main factor determining whether pancreatic cancer cells increase autophagy levels is their ability to detect the extracellular ...