Although the CRISPR/Cas9 gene editing system is in wide use, its molecular basis still needs to be better understood. Of particular interest are molecular details that could account for the ...

As part of these so-called CRISPR-Cas systems, a CRISPR ribonucleic acid (crRNA), which serves as a "guide RNA," recognizes regions of a foreign genome, such as viral DNA.

CRISPR is a technology that can be used to edit genes and, as such, will likely change the world. The essence of CRISPR is simple: it’s a way of finding a specific bit of DNA inside a cell. After that ...

As CRISPR gene editing marches closer to the clinic, several researchers have been tinkering to unleash the DNA editor on another nucleic acid: RNA, the intermediary messenger between DNA and ...

RNA gene scissors (CRISPR-Cas13) are gaining significant attention as a next-generation gene therapy with fewer side effects. They can suppress infection by eliminating viral RNA, such as in ...