DNA damage has been associated with aging and disease. Double-strand breaks are one of the worst forms of damage. New research shines a light on the repair process.

Theoretical physicists like to play with very unconventional toys. Researchers have adopted a seemingly playful approach to examining what happens to a double stranded molecule of DNA when it is ...

The high-molecular-weight DNA isolated from cells is prepared in agarose plugs or inserts and can then be incubated with DNA-modifying enzymes such as restriction endonucleases.

Carnegie Mellon University researchers have developed a synthetic molecule that can recognize and bind to double-stranded DNA or RNA under normal physiological conditions. The molecule could ...

DNA, or deoxyribonucleic acid, is the hereditary material found in nearly all living organisms. It carries the genetic instructions for the development, functioning, growth, and reproduction of all ...

(The DNA molecule is itself a double strand held together by these building blocks and wrapped together like a helix.) The new visualization of the G-quadruplex is detailed this week in the ...

Cells primarily repair double-strand breaks by either rejoining the broken DNA ends or by using another DNA molecule as a template for repair.