UCSF scientists have used a high-throughput CRISPR-based technique to rapidly map the functions of nearly 500 genes in human cells, many of them never before studied in detail.

The research team led by Itakura gained new knowledge of the functions that human cells have for maintaining homeostasis through experiments in petri dishes.

Miniature models of the brain have revealed a "previously unappreciated" role of microglia, a type of cell found within the ...

Thousands of previously “invisible” microproteins—tiny chains of fewer than 100 amino acids—can profoundly change human ...

A high-resolution spatial map of the human hypothalamus makes it possible to identify specific cells, determine their exact location and analyze their neighboring cells. The cell atlas, called ...

It turns out that not all the hairlike cilia projecting from the surfaces of many cells in the human body are equal—there are the myriad ones for sweeping, swimming and other functions, and then ...

"Our findings demonstrate that CLOCK has undergone evolutionary gains of extra-circadian function, and that these functions may contribute to human-specific brain specializations," said Konopka.