UB neuroscientists conducting basic research on ion channels have demonstrated a process that could have a profound therapeutic impact on pain. Targeting these ion channels pharmacologically would ...

Researchers have developed a method for identifying small molecules that bind metal ions. Metal ions are essential in biology. But identifying which molecules—and especially which small ...

Researchers have identified two ion channel switches that regulate the release of dopamine in the brain, a first step that might one day lead to therapeutics for a wide range of diseases and disorders ...

UT Southwestern Medical Center researchers have identified an ion channel required for brain cells to suppress eating behavior in response to the hormone leptin or to the anti-obesity drug lorcaserin.

Researchers from the Icahn School of Medicine at Mount Sinai have identified a drug that works against depression by a completely different mechanism than existing treatments. Their study showed that ...

Tandem mass spectrometry is a powerful tool in proteomics. By ionizing peptides and then fragmenting those ions into smaller product ions, researchers can determine the biomolecules’ amino acid ...

Clinical trial results provide rationale for continued study of the KCNQ type of ion channel. Researchers from the Icahn School of Medicine at Mount Sinai have identified a drug that works against ...