To create A1 lipid nanoparticles for delivering mRNA to target cells, scientists at the University of Pennsylvania used A3 coupling. A3 refers to the amine–aldehyde–alkyne coupling reaction, which the ...

Scientists have developed a method for analysing the structure of lipid nanoparticles that could be used to improve vaccine and drug delivery, targeting a wide range of health issues. A team led by ...

Lipid nanoparticles (LNPs) are one of the most exciting technologies in drug delivery. LNPs protect and deliver genetic material into cells, allowing a large spectrum of RNA therapeutics, including ...

Schematic illustration showing the classification of lipid‐based nanocarriers (LBNCs) (including liposomes, micelles, nanoemulsions, SLNs/NLCs, LNPs, BLNs, SRLNCs) and their targeted delivery to ...

Lipids are fatty compounds that perform a range of essential functions in the body. Phospholipids, steroids, and triglycerides are examples of lipids. Although lipids play an essential role in the ...

What the research is about The cell membrane that surrounds our cells may look smooth and simple, but it is actually ...

Dried mRNA vaccines can match standard injection without cold storage when a polymer matrix at the right ratio prevents the ...