Innovative bioprocessing technologies are needed to make monoclonal antibody (mAb) production cheaper, according to new research, which suggests lowering the cost of goods (COGs) for mAb-based ...

A hybrid modeling framework to optimize Chinese hamster ovary cell cultures for monoclonal antibody (mAb) production reduces the number of modeling parameters needed while returning results that ...

The long journey from cell culture to a purified monoclonal antibody (mAb) involves many sample processing steps, with clarification and filtration playing significant roles. However, clogs, complex ...

The brain of a rat in which a fluorescent protein has been used to highlight transplanted human brain cells - Copyright Stanford University/AFP Sergiu PASCA The brain ...

Antibody engineering and production are essential tools in drug discovery, providing powerful and specific therapeutics and diagnostic/prognostic materials for various diseases. Antibodies are ...

Many early workflows lack scalability, relying on temperature-sensitive steps, outdated purification tools or unnecessary customization. These design flaws often derail timelines and inflate costs ...

Antibodies are Y-shaped protective proteins manufactured by B lymphocytes in reaction to invading pathogens. When B lymphocytes encounter foreign antigens expressed by antigen-presenting cells (e.g.

Monoclonal antibodies (mAbs) have revolutionized modern medicine, offering precision therapies for cancer, autoimmune disorders, infectious diseases, and numerous other advantages. The global mAb ...

Investigators from the European Brain Research Institute (EBRI) recently presented data on an immunotherapeutic approach based on the monoclonal antibody (MAb) 12A12 for treating Alzheimer’s disease ...

Real-time and in-line accurate measuring of protein (monoclonal antibody, or mAb) concentration has been shown across a wide dynamic range (0–135 g/L) through the ...