Mathematical models have become an integral part of cancer biology. They are useful tools for deriving a mechanistic understanding of dynamic processes in cancer. The somatic evolutionary process, ...

Human cancers are thought to be sustained in their growth by a pathologic counterpart of normal adult stem cells: cancer stem cells. This concept was first developed in human myeloid leukemias and is ...

Abstract: An oncological antibody-drug conjugate (ADC) is a medicine that combines the receptor-targeting property of a monoclonal antibody with the cell-killing property of a cytotoxic small molecule ...

Some states of affairs are so ubiquitous in the natural world that – much like the air we breathe – we stop noticing their existence or finding them particularly strange. The effects of aging are good ...