In a paper recently published in Neuron, researchers from the group of Botond Roska at IOB reveal how different cell types in cortex change their activity during general anesthesia, helping to ...

We conclude that brain states are shaped by local circuit mechanisms, large-scale connectivity and neuromodulation. A unified multiscale theory of cortical dynamics is relevant not only for ...

(A) Schematic diagram of the experimental system that detects calcium release from the endoplasmic reticulum by each ryanodine receptor. (B) Isoflurane selectively activates RyR1 (mean ± standard ...

The cerebral cortex is thought to be the seat of conscious processing in the brain. Rather than being inactivated, specific cells in the cortex show higher spontaneous activity during general ...

Propofol is the most commonly used drug to induce general anesthesia. Despite its frequent clinical application, it is poorly understood how propofol causes anesthesia. Propofol is the most commonly ...

The new approach involve studying the mechanism of anesthetics from the anatomical to the molecular level to sort out the "why" and develop a way to remove pain and allow for live-saving treatments as ...

‌Local anesthesia numbs a part of your body so that your doctor can stitch up a wound or take a biopsy without you feeling any pain. Unlike general anesthesia, where you are put to sleep during a ...

“I wanna be sedated,” sang Joey Ramone in the 1978 song of the same name. But Joey didn’t know that not all sedatives affect the brain in the same way — let alone the mechanisms that cause those ...

Anesthesia is a type of medication that prevents people from feeling pain during or following surgery. There are four main categories of anesthesia: local, regional, general, and sedation. Share on ...

There are four types of medical anesthetics used by medical professionals, depending on what type of procedure you are having. Share on Pinterest Santi Nuñez/Stocksy United Anesthesia is used to ...