Metastases are the principal cause of death in patients with cancer. Recent advances bring hope that it will be possible to identify the molecules and processes involved in metastasis, and this new ...

The Molecular Basis of Cancer program provides students with in-depth understanding of academic and practical knowledge in basic and translational cancer research, with emphasis in molecular targets ...

Ovarian cancer shows considerable heterogeneity in its sensitivity to chemotherapy both clinically and in vitro. This study tested the hypothesis that the molecular basis of this difference lies ...

Gastric cancer is the top lethal cancer in Asia. As the majority of cases present with advanced disease, conventional therapies have limited efficacy. Emerging modalities provide promise to combat ...

Studying a deadly type of breast cancer called triple negative, Johns Hopkins Medicine scientists say they have identified key molecular differences between cancer cells that cling to an initial ...

In recent decades, there has been focused research on the molecular mechanisms of cancer to improve drug delivery and survival rates.

Since the work of Paget more than 100 years ago, pathologists have recognized that the movement of cancer cells is not random and that different types of cancer have different destinations.

HR biomarker testing is primarily done via immunohistochemistry (IHC) and detects the presence of estrogen receptors (ERs) and progesterone receptors (PRs) on cancer cells. Breast cancers that test ...

Cancer drug development is leading the way in exploiting molecular biological and genetic information to develop 'personalized' medicine. The new paradigm is to develop agents that target the ...