A new review article published in Genes & Diseases explores the intricate relationship between non-coding RNAs and oxidative stress in cancer progression shedding new light on the mechanisms that ...

Non-coding RNA is a ribonucleic acid molecule that is generated from the non-protein coding DNA sequence, that makes up 98-99% of the human genome. A plethora of different types of functional ...

The human genome contains about 20,000 protein-coding genes, but that only accounts for roughly two percent of the genome. For many years, it was easier for scientists to simply ignore all of that ...

“There is strong debate in the scientific community on whether the thousands of long non-coding RNAs generated from our genomes are functional or simply byproducts of a noisy transcriptional machinery ...

Long non-coding RNAs (lncRNA) are sections of RNA over 200 nucleotides in length that are not translated into proteins, remaining in the nucleus following transcription in relatively low concentration ...

Schematic representation summarising MASLD-associated long non-coding RNAs (lncRNAs) and their relevant targets in hepatocytes: human leukocyte antigen (HLA) complex group 18 (HCG18), nuclear enriched ...

Researchers have identified a portion of the human genome known as PTCHD1-AS on the X chromosome that does not code for ...

Non-coding RNAs and oxidative stress work together in various stages of cancer progression, including cancer cell growth and reproduction, cancer cell invasion, tumor microenvironment shaping, ...

As a PhD student at the University of Münster in the early 2000s, Sven Diederichs would bike three kilometers each morning to a compact lab in a brick building on the hospital campus. There, he’d ...

A new study identifies PTCHD1-AS as a key non-coding gene that shapes social and repetitive behaviors in autism without affecting cognition.