The new workflow was adapted from an enzymatic DNA tagging technology, DNA-TAG, previously developed in the Devaraj lab. In ...

A recent international research project has used advanced microscopy techniques and computational modeling to discover why ...

Gene therapy holds the promise of preventing and curing disease by manipulating gene expression within a patient's cells. However, to be effective, the new gene must make it into a cell's nucleus. The ...

Cancer cells with a cell nucleus that is easily deformed are more sensitive to drugs that damage DNA. These are the findings of a new study by researchers at Linköping University in Sweden. The ...

Researchers have used advanced microscopy and computational modeling to show how herpesvirus infection affects host-cell nucleus structure.

Researchers at the Francis Crick Institute have shown that the 'pacemaker' controlling yeast cell division lies inside the nucleus rather than outside it, as previously thought. Having the pacemaker ...

Cancer cells are subjected to high mechanical pressure that leads to a rupture of the nuclear envelope when migrating through narrow tissue structures, as in the case of metastasis. DNA would normally ...

Synthetic hydrogel-based assay to study 3D confined cell migration. Credit: Science Advances (2024). DOI: 10.1126/sciadv.adm9195 Eukaryotic cells—that is, cells with a nucleus—possess an astounding ...

(Nanowerk News) Imagine trying to poke a hole in the yolk of a raw egg without breaking the egg white. It sounds impossible, but researchers at the University of California San Diego have developed a ...