The term lysogenic refers to the ability of bacteriophages to assume a dormant state, referred to as a prophage, in the bacterial cell. Lysogeny is characterised by the integration of the viral DNA ...

Phage display is an analytical technique used to study protein-protein interactions and the relationship between a protein and the encoding DNA. Phage display begins by incorporating the protein of ...

In the early and mid-1980s, scientists used phages to express recombinant proteins. The protein was retained inside the virions, so screening required growing viral plaques, creating a stamp of these ...

Determining functions of novel gene products identified in genome sequencing efforts has become an important scientific challenge. Identifying proteins that interact with novel gene products can help ...

Researchers have mapped out what a commonly-used form of phage looks like, which will help design better uses in future. New insights into the structure of phages will enable researchers to develop ...

When a person receives a cancer diagnosis, treatment can often include chemotherapy. This method of treating cancer also can affect healthy cells. But what if there was a drug on the market that, ...

Antibiotics are widely used in clinical treatment and animal production as an effective means to combat microbial infections. Antimicrobial peptides, as potential alternatives to antibiotics, have ...

Recent advances in phage display for molecular evolution incorporate deep sequencing to enable greater library coverage. However, severe gaps and limitations associated with next generation sequencing ...

Aga2-fusion protein binding to yeast cell by Aga1. Image provided by Invitrogen. Phage display systems, reviewed in a recent issue of The Scientist, 1 have proven enormously useful for the detection ...

Mapping the individual amino acids where antibodies bind (epitopes) to target viral proteins (antigens) is crucial to predicting how target proteins may evolve to escape antibody binding, improve ...