The flow cytometry-based assay measures the expression of the protein FcyR11a as a biomarker for cardiovascular risk.

Although early indications suggest that these new therapeutics are well tolerated, stimulation of c-Mpl may potentiate platelet activation and trigger thrombosis, a particular concern for older ...

platelets, and leukocytes. Endothelial cells are also likely to participate in activation, both by production of cellular fibronectin and via conversion of transforming growth factor (TGF)-beta ...

[59] Larger trials are necessary to confirm the existence of platelet resistance to prasugrel and to describe the possible underlining mechanisms. Elinogrel (PRT060128 or PRT128) (Figure 3 ...