Scientists say their work on a critical step in DNA replication will provide new insights into a fundamental process of life and driver of many different diseases, including cancer. They report ...

A team has unlocked a decades old mystery about how a critical cellular process called DNA replication is regulated.

The manipulation of DNA replication and the adoption of advanced gene-editing technologies illustrate a remarkable convergence of scientific innovation and ethical considerations.

To ensure precise duplication of chromosomal DNA, replication origins are 'licensed' for replication during late mitosis and early G1 by loading complexes of the Mcm2–7 proteins. The licensing ...