Before cells divide, their DNA must be precisely copied in a process called replication. This research focused on a ring-shaped enzyme called the minichromosome maintenance or MCM complex that ...

The proteins that drive DNA replication—the force behind cellular growth and reproduction—are some of the most complex machines on Earth. The multistep replication process involves hundreds of ...

DNA replication is closely linked to the process of cell division. Before a cell can divide into two daughter cells, it must ensure that each daughter cell receives an exact copy of the genetic ...

The team speculate that the reverse-direction enzyme is not used in DNA replication because it requires a structurally complicated process.

DNA replication likes one direction. Not the boy band, but rather it prefers to replicate in a certain direction over the other. Publishing their findings in Science Advances, scientists have ...

Failures in DNA replication can lead to cancer, birth defects or other harm Video shows single pieces of double-helix DNA being copied Single-molecule view gives new insights into this process ...

GapR acts as a clamp on the DNA backbone, not the bases, when DNA is over twisted. When relaxed, the DNA doesn’t fit into that clamp, suggesting that GapR only sits on DNA when the topoisomerase is ...

DNA replication is the biological process by which an exact copy of a deoxyribonucleic acid (DNA) molecule is created and it is the basis for biological inheritance. Each of the two strands of the ...

Initiator proteins are key components of the DNA replication machinery that determine where initiation will occur. In the past few years, due to a greatly improved understanding of what viral ...

Scientists reveal a crystal structure that illustrates a mechanism that powers and possibly starts DNA replication.