SNP-based microarrays identify unbalanced chromosomal abnormalities (loss and/or gain of DNA) in patients with unexplained abnormal phenotypes such as intellectual disability, dysmorphic features ...

While microarrays provide information about the presence or absence of a genetic variant, the Diversity SNP panel produces dynamic, multi-faceted information across a broad spectrum of the population.

SNP microarrays are capable of detecting a large number of subtle DNA alterations and/or abnormal alterations related to chromosome copy number (aneuploidy) or chromosome structural rearrangements. In ...

Thus, it is reasonable to ask how powerful—and useful—could be a large-scale association study using SNP microarrays in crosses between divergent outbred populations.

The first use of SNP microarrays in a large autism study was by the Autism Genome Project, who used Affymetrix 10K SNP microarray data to perform high-resolution linkage analysis in over 1000 ...

SNP array karyotyping has several advantages over fluorescence in situ hybridization (FISH) testing, including the detection of acquired uniparental disomy (UPD) and of atypical deletions.

The SNP Array 6.0 is a single microarray that measures more than 1.8 million markers for genetic variation, according to the company. It consists of 906,600 SNPs and 946,000 copy-number probes.

Background: SNP microarray can detect Copy Number Alterations (CNAs) which could be predictive of response and can help define therapeutic strategies. Our aim is to improve conventional cytogenetic ...