Am J Health Syst Pharm. 2010;67(22):1920-1928. Due to the high osmolarity of hypertonic saline, infusion through a central line is preferred to minimize phlebitis. Most studies used a 7.5% hypertonic ...
Trials evaluating the use of hypertonic saline solutions for resuscitation after traumatic injury have not shown an overall mortality benefit compared with isotonic fluid administration. The largest ...