In SetPoint you need to set the buttons to key presses that you don't use when you're playing. Like N, J, K, L, ;, etc. You can either do this for all applications, or figure out which .exe is running ...
I’ve used the Logitech MX Master 3 as my primary productivity mouse since it came out in 2019. I’ve tested dozens of mice since, but none juggled a decent number of programmable buttons, advanced ...