Oocyte-specific AGK deficiency causes multifaceted mitochondrial dysfunction and follicular development arrest, providing insights into the molecular mechanisms and a potential diagnostic and ...

A new artificial intelligence-powered tool called MISO (Multi-modal Spatial Omics) can detect cell-level characteristics of cancer by looking at data from extremely small pieces of tissue-some as ...

I was a molecular geneticist doing a lot of single-cell assays. Despite this, my main interests always pointed back to the tissue, because disease pathogenesis involves more than just individual cell ...

This illustration summarizes how integrated spatial transcriptomics, single-cell transcriptomics, single-cell epigenomics, and spatial epigenomics enable multi-dimensional profiling of the tumor ...

Spatial omics is a new generation of technologies that allow scientists to study cells in their original location within tissues (without isolating or moving them from their environment). Just as a ...

When scientists look through a microscope, they often see cells in isolation: either frozen in time within a thin slice of tissue or removed entirely from the environment they once called home. These ...

A novel spatial transcriptomics atlas developed by Northwestern Medicine scientists may improve the understanding of niche ...

Spatial omics is a suite of molecular technologies that measure and map the distribution of genes, proteins, and metabolites while preserving their native spatial context and cellular organization, ...

IRB Barcelona launches Spain’s first fully integrated spatial omics platform. Spatial omics is a new generation of technologies that allow scientists to study cells in their original location within ...

The STELLARIS confocal platform offers significant advancements for high-multiplex strategies, integrating a tunable white light laser (WLL) with an excitation range from 440 nm to 790 nm and up to ...

Petosemtamab (MCLA-158) with pembrolizumab as first-line (1L) treatment of PD-L1+ recurrent/metastatic (r/m) head and neck squamous cell carcinoma (HNSCC): Phase 2 trial. Cetuximab plus dalpiciclib in ...