Tumors trigger T-cell exhaustion through a TSP-1–CD47 signaling pathway. Blocking it can restore immune strength and improve cancer treatment.
The field of tissue-immune interactions has undergone significant transformation as emerging evidence demonstrates the centrality of local microenvironments ...
A recent Science study explored how intranuclear metabolic enzymes establish the link between locus-specific epigenetic reprogramming of T cells and nutrient availability. Persistent antigen ...
Israel Institute of Technology Faculty of Biology have identified a unique mechanism involved in the aging of the immune ...
Study reveals that moderate fever temperatures (39°C) improve metabolism, proliferation, and effector function of CD4 T cells while reducing regulatory T cell suppression. Study: Subset-specific ...
RegCell, Inc. a biotechnology company developing first-in-class therapies for autoimmune diseases and transplantation with its epigenetic reprogramming platform leveraging the natural biology of ...
T-cell lymphoma has remained an exceptionally challenging disease with limited therapeutic advances for far too long,” said Nicholas Siciliano, Ph.D., Chief Executive Officer of Vittoria ...
Share on Facebook. Opens in a new tab or window Share on Bluesky. Opens in a new tab or window Share on X. Opens in a new tab or window Share on LinkedIn. Opens in a new tab or window While the use of ...
Active component of HCW9302 is interleukin-2 -- cytokine that maintains proper numbers and functions of regulatory T cells to control excessive inflammation Gateway to development of a first-in-kind ...
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