The biopharmaceutical industry produces highly complex and effective medicines to treat challenging diseases. However, changing dynamics in the industry are placing significant pressure on existing ...

For decades, therapeutic monoclonal antibody (mAb) production relied on traditional batch-based manufacturing using stainless steel systems. But as biopharmaceutical pipelines grow to meet rising ...

Breakthrough technology eliminates the recirculation loop to reduce in-process volumes and increase final product concentration, both at high yield PORT WASHINGTON, N.Y., April 20, 2010 - As ...

NEW YORK - Filtration specialist Pall used Interphex as the launching pad for a single-pass tangential flow filtration product and a filter integrity test instrument. The Cadence system incorporates a ...

Upstream titers of 3–5 g/L, and up to 10–13 g/L, are outpacing downstream capacity, creating chromatography, filtration, and UF/DF throughput bottlenecks that elevate cost and delay timelines. Complex ...

Biopharmaceutical downstream processing requires precise control of multiple unit operations—from chromatography and filtration to viral inactivation—to ensure product quality and therapeutic efficacy ...

In this presentation, we will present a novel way of concentrating samples and performing buffer exchange using the µPULSE —TFF System. The instrument is a fully automated walk-away system that uses ...

Over the years, a variety of pump technologies have been tested or used for virus filtration, chromatography, and TFF processes. Lobe and peristaltic pumps are two of the most popular choices of ...

Viral vectors are key delivery tools for advanced therapies, enabling gene transfer to treat inherited disorders, cancer and other serious diseases. Despite rapid clinical progress, manufacturing ...