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To analyse these potential changes in gene expression more comprehensively, we are using the recently described cDNA microarray to look at cells transduced with a neoR-expressing retroviral vector.
The DNA copy that is made, called complementary DNA (cDNA), is then applied to the microarray. The cDNA binds to complementary base pairs in each of the spots on the array, a process known as ...
Background: Oligonucleotide and cDNA microarrays are commonly used to profile gene expression in biological samples. These arrays are frequently expensive to design and print, limiting useful ...
CDNA microarrays hold great promise for characterizing disease and performing genetic studies, but they're not exactly an out-of-the-box technology just yet. Often the scientists must prepare their ...
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