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Raina Biosciences Inc. (Raina), an mRNA technology and therapeutics company, has released data from its generative AI ...
The new CBC-ALYREF structure revealed molecular insights into the ALYREF-mediated recruitment of mRNA export machinery to the 5' end of nascent mRNA transcripts.
Based on this structure, the researchers proposed a model of how the mRNA slots into a channel in the small ribosomal subunit, and a mechanism for how the mRNA might be pulled through the ribosome ...
The treatment suppressed tumors in mouse models of colon cancer and melanoma, and it worked even better when combined with checkpoint inhibition, they reported in the journal Science Translational ...
The popularity of mRNA-based therapeutics has surged over the past few years. To ensure the safety of these treatments, scientists need to analyze the characteristics of the manufactured molecules, ...
PepMLM generates binders to challenging therapeutic targets across cancer and neurological disease using protein sequence and no structure.
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