A new study by researchers from the Gwangju Institute of Science and Technology in the Republic of Korea has revealed the mechanism of DNA repair by enzymes exonuclease III and polymerase I by ...

One method to repair such damage that all organisms have evolved is called base excision repair. In BER, special enzymes known as DNA glycosylases travel down the DNA molecule scanning for these ...

Excision Repair Pathways The excision repair pathway is the predominant, and perhaps universal, mechanism for the maintenance of genomic integrity.

Introduction Base excision repair (BER) is a major DNA repair pathway for repair of base damage including 8-oxoguanine and thymine glycols caused by oxidation.

He then went on to discover one of these mechanisms, base-excision repair, which removes incorrect bases from the genome and replaces it with the correct one (see video below). Base-excision repair.

Those single-base errors usually occur spontaneously. But another mechanism of DNA repair, nucleotide excision (discovered by Aziz Sancar), targets more extensive genetic damage caused by UV ...

Better understanding of the mechanisms involved in DNA repair may pave the way for developing inhibitors to improve the effectiveness of radiation therapy.