DNA phosphorothioate modification is a distinctive epigenetic alteration in which a non‐bridging oxygen atom within the DNA sugar-phosphate backbone is replaced by sulphur.

Until now, these DNA modifications have been discovered by chance, as scientists uncovered unexpected signals in chemical analyses of DNA. However, a new approach from MIT, the University of Florida, ...

5 latest biotechnology breakthroughs, from genome sequencing to microbiome manipulation, revolutionizing medicine, ...

Long-term, heritable changes in gene activity fundamentally shape our biology, trigger many of our diseases, and set the clock on how we age. Now, a team of U of U Health scientists is starting an ...

A UCLA-led study has provided an unprecedented look at how gene regulation evolves during human brain development, showing how the 3D structure of chromatin - DNA and proteins - plays a critical role.

Researchers have revealed a previously unknown DNA modification in zebrafish - one of human's distant evolutionary cousins.

UCLA researchers analyzed a certain type of DNA marker across hundreds of mammal species and found associations with traits such as lifespan, weight and age. The study, published in August ...