During transcription, the first step in gene expression, RNAPs "read" DNA sequences and assemble messenger RNA (mRNA), which in turn serves as the template for the proteins necessary for life.

Scientists have elucidated the first steps of transcription-coupled repair (TCR), a critical but still mysterious mechanism of DNA repair. When genetic information is being transcribed from DNA to ...

Transcription factors regulate gene expression by binding specific sequences on DNA, which is an essential step to producing messenger RNAs from protein-coding genes.

A new study has described E. coli RNAP in the act of opening the transcription bubble. The findings, captured within 500 milliseconds of RNAP mixing with DNA, shed light on fundamental mechanisms of ...

The OnScreen Gene Transcription app for the iPad does an excellent job bringing DNA transcription to life via an interactive 3-D DNA model and a simulation of the transcription process.