A recent study identified a non-insulin-related protein that can activate the human insulin receptor, which could lead to the development of an insulin-mimicking oral pill and replace the need for ...

Normally, the human insulin receptor is activated by the same region of insulin that links the molecules to one another—but to create the snail-human insulin hybrids, this segment has been removed to ...

If insulin can’t get out of blood vessels, it can’t act in its target tissues. “Endothelial cells are full of insulin receptors,” says Stefan Offermanns, who led the study.

Researchers investigate the underlying mechanisms of endothelial insulin resistance involved in obesity-associated diabetes.