Research Article Published: 18 March 2004 Efficient lentiviral transduction of Herpesvirus saimiri immortalized T cells as a model for gene therapy in primary immunodeficiencies M G Toscano, C ...

Takara Bio’s dissolvable, microfluidic gene delivery enhancer transforms viral transduction to enable advances in cell and gene therapy research.

Novel sponge developed by Takara Bio USA enables effective preparation of T cells for CAR T-cell therapy research from primary PBMC samples.

The investigators showed that lentiviral transduction was enhanced by CsH and led to therapeutic levels of expression of HbAs3.

A new study of the San Raffaele Telethon Institute for Gene Therapy show that only 15–20% of hepatocytes in newborn mice are responsible for generating over 90% of the adult liver mass: these findings ...

Lentiviral transduction is a popular and powerful gene delivery method for downstream applications such as cell line generation, therapeutic model generation and CAR-T research. However, current ...

MxV-G is a novel fusogen for lentiviral packaging that achieves higher vector titers and enhanced transduction efficiency.The detargeted MxV-G mutant abolishes native receptor binding while ...

Dr. Christian Thirion, CEO and founder of SIRION explains: “LentiBOOST™ improves lentiviral transduction of difficult cell types like hematopoietic stem cells, and in addition generates stable ...

For example, spinoculation—the use of a centrifuge to bring lentivirus and cells in closer proximity—and chemical enhancers are commonly used techniques to increase transduction efficiency.