Researchers have uncovered a key control mechanism of DNA replication with potential implications for better understanding how cells maintain genetic information to prevent diseases or cancer.

DNA replication is a fundamental biological process that enables the accurate duplication of an organism’s genetic material. This intricate mechanism ensures that each new cell receives a ...

Replication that proceeds in an unusual bubble-like mode then copies hundreds of kilobases of DNA from the donor DNA through the telomere at the ends of chromosomes.

DNA replication likes one direction. Not the boy band, but rather it prefers to replicate in a certain direction over the other. Publishing their findings in Science Advances, scientists have ...

Researchers from Osaka University in Japan have uncovered a key control mechanism of DNA replication with potential implications for better understanding how cells maintain genetic information to ...

Mitochondrial transcription elongation factor maintains the balance between transcription and replication of mitochondrial DNA offering insights into potential treatments for mitochondrial disease ...

This suggests that during evolution, the use of replication origins became more controlled by epigenetic mechanisms affecting chromosome dynamics and expression than by DNA synthesis per se.

The DNA replication process is carried out by multiple protein complexes with highly specialized functions, including the unwinding of DNA and the copying of the two unwound DNA strands.

RNA-binding proteins use a dual binding mechanism involving zinc finger (ZnF) domains and intrinsically disordered regions ...

Researchers from Osaka University in Japan have uncovered a key control mechanism of DNA replication with potential implications for better understanding how cells maintain genetic information to ...