Type 1 diabetes generally results from autoimmune destruction of pancreatic islet ß-cells, with consequent absolute insulin deficiency and complete dependence on exogenous insulin treatment. The ...

A man with type 1 diabetes produced his own insulin after receiving the world’s first CRISPR-edited islet cell transplant, ...

First, the team engineered the gene for human proinsulin to insert a tag that makes the protein fluorescent, but does not interfere with the production, function or secretion of insulin.

We evaluated the ability of the skeletal muscle to release human insulin after electrotransfer (ET)-enhanced plasmid DNA injection in mice.

Stem cell researchers at Harvard University have devised a method for creating large quantities of human insulin-producing beta cells, which could soon lead to a cure for type 1 diabetes as well ...

People with type 1 diabetes must constantly rely on insulin injections or pumps, usually for the rest of their life after diagnosis. The autoimmune disease destroys the cells that produce the hormone, ...

First, the team engineered the gene for human proinsulin to insert a tag that makes the protein fluorescent, but does not interfere with the production, function or secretion of insulin.

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