She was 44 when she was diagnosed with systemic scleroderma," he told NIH Medline Plus Magazine in 2019. "She got treatment, but it was just treating her symptoms with drugs like prednisone and ...

Sclerodactyly is a tightening and thickening of the skin of the fingers as a result of systemic scleroderma. It can cause the fingers to curl inward and the hands to form a clawed shape.

Finally, scleroderma can affect patients very differently and individually, further confusing the picture. Although each patient may present differently, there are several patterns of symptoms ...

Using mice, lab-grown cells and clues from a related disorder, researchers have greatly increased understanding of the causes of systemic sclerosis, showing that a critical culprit is a defect in ...

CREST syndrome is a condition that affects the connective tissue of the body. It is a form of systemic sclerosis, which affects the skin, causing it to harden and tighten. Learn more.