The Tennessee Titans, led by quarterback Cam Ward, face the San Francisco 49ers, led by quarterback Brock Purdy, on Sunday, Dec. 14, 2025 at Levi’s Stadium in Santa Clara, Calif.

Hours after they were officially eliminated from postseason contention, the Minnesota Vikings dealt a blow to Dallas' playoff odds by beating the Cowboys 34-26 on “Sunday Night Football.”

The Cowboys lead the all-time regular season series between these teams, 15-12, and have won five of their six most-recent meetings.

The Tennessee Titans kept pace in the race for the No. 1 pick in the 2026 NFL draft.

Jeffery Simmons took over the game for the Tennessee Titans in one three-play stretch in the opening minute of the fourth quarter.

With just four weeks left in the regular season, San Francisco has put together a 9-4 record and currently holds the sixth seed in the conference.