“the lagging strand polymerase synthesizes DNA faster than the leading strand polymerase.” DNA replication occurs at the replication fork, which forms when DNA is unwound by a helicase into ...

On one strand — the “leading strand” — the polymerase can move continuously, leaving a trail of new double-stranded DNA behind it. But on the other, “lagging strand,” the polymerase has to move in ...

Stop and Go Instead, the progress of the “lagging strand” polymerase looks a lot like stop and go traffic, stopping unpredictably and starting up again at random speeds that can vary tenfold.

Thus, at any given time the lagging-strand polymerase could be moving faster than the leading-strand polymerase and vice-versa. To prevent the accumulation of unreplicated gaps in the nascent DNA, ...

To study DNA replication in vitro, Yeeles assembled replisomes with Saccharomyces cerevisiae proteins capable of performing complete leading- and lagging-strand replication.

First Look: DNA Replication For the first time ever, scientists have captured a single DNA molecule replicating on video — and it's changing the way we think about the entire process.

The scientists determined that Mrc1 and Mcm2 form a co-chaperone complex, ensuring distribution of histones to the lagging strand during DNA replication.

As for the lagging-strand, DNA synthesis should not have a problem. It could start the last Okazaki fragment somewhere along the 3' overhang.

As for the lagging-strand, DNA synthesis should not have a problem. It could start the last Okazaki fragment somewhere along the 3’ overhang.