Robert F. Kennedy, Jr overcame some initial Republican skepticism to be confirmed as Secretary of Health and Human Services. GOP Senator Mitch McConnell was the lone Republican to vote against him. NBC News' Ryan Nobles reports.

We discuss All Things New England Sports with John Tomase on “Wicked Sports Weekend.” Republican Sen. Mitch McConnell is announcing on Thursday that he won't seek reelection next year, ending a decadeslong tenure as a power broker who championed conservative causes but ultimately ceded ground to the fierce GOP populism of President Donald Trump.

The new Republican Party does not include many Republican Liz Cheney- and Mitch McConnell-types who swam in the swamp for years for their own financial gain. "Life-long public servants" like Chuck Schumer ($81 million net worth) and Mitch McConnell (with tens of millions),

Mitch McConnell announced the impending close of his four-decade Senate career Thursday, underscoring a remarkable legacy of turning American government rightward but also capping a fading era in Republican politics.

The fight to succeed longtime Republican Senate leader Mitch McConnell in Kentucky began on Thursday, with Daniel Cameron throwing his hat in and others announcing their consideration.

Sen. Mitch McConnell was a generational force for the Republican Party — using procedural tactics and political will to stymie much of former President Barack Obama’s agenda, hand President Donald Trump key first-term political victories and deliver a 6-3 conservative Supreme Court majority.

Senator Mitch McConnell broke with his fellow Republicans again by voting "no" on Robert F. Kennedy, Jr. as HHS Secretary. Brendan Buck, former aide to Speakers Ryan and Boehner, joins Chris Jansing to share his analysis of the Republican Party and McConnell defying President Trump's picks.

"My current term in the Senate will be my last," Republican Sen. Mitch McConnell said during a speech on the Senate floor. First elected in 1984, McConnell intends to serve the remainder of his term ending in January 2027.

Kennedy will oversee some of the federal government’s largest public health agencies, including the NIH, FDA, and the Centers for Medicare and Medicaid Services

While he championed conservative causes, McConnell ultimately saw his influence challenged by the rise of Trump-era GOP populism.

The Kentucky senator is stepping down after a consequential career. Whether Americans benefited from his triumphs, however, is another matter entirely.