Unexpected slowdowns or spikes in this signal were often interpreted as knots in DNA. But now, a new study published Aug. 12 ...

DNA doesn’t knot under stress. A new study finds it coils into plectonemes, reshaping models of genome mechanics. For decades ...

For decades, large stretches of human DNA were dismissed as "junk" and considered to serve no real purpose. In a new study ...

The non-coding genome, once dismissed as "junk DNA", is now recognized as a fundamental regulator of gene expression and a ...

A new study shows that repetitive DNA, once dismissed as “junk,” plays a critical role in shaping the human brain.

They are called plectonemes. They are the analog of the twisted tangles of telephone cords, and can form in DNA that is pulled through a nanoscale channel. This is the finding of a study led by Ulrich ...

For decades, large stretches of human DNA were dismissed as “junk,” thought to serve no real purpose. In a new study in Cell ...

How chromatin responds to transcription-blocking DNA lesions is unclear. This study reveals that RNA polymerase II (RNAPII) ...

The accuracy of spatial gene expression profiles generated by probe-based in situ spatially-resolved transcriptomic technologies depends on the specificity with which probes bind to their intended ...

This study presents a valuable comparison of the efficiency and precision of two prime editing methods to introduce single-nucleotide variants and longer exogenous DNA sequences into the zebrafish ...