Red arrows indicate the DNA repair pathways that are known to aid bacterial survival as persisters and gamblers in the ...

Bacteria frequently encounter adverse environmental conditions, such as nutrient scarcity and antibiotic exposure, which can induce DNA damage ...

This important work advances our understanding of DNA methylation and its consequences for susceptibility to DNA damage. This work presents evidence that DNA methylation can accentuate the genomic ...

They discovered that DNA packaging sends signals through an unusual pathway, affecting the cell's ability to divide ... Her group investigates chromatin dynamics during DNA replication and repair. The ...

Learn about HMGB1's crucial role in liver diseases, its pathways and therapeutic potential that can treat liver diseases.

MSK researchers discovered that the innate immune system's chronic activation due to issues in the Mre11 complex can lead to ...

A groundbreaking study by researchers from the University of Delaware College of Health Sciences and the National Institute ...

Researchers at the Center for Genomic Regulation (CRG) reveal that metabolic enzymes known for their roles in energy ...

StitchR makes it possible to deliver larger payloads with current vectors, expanding the list of diseases targetable by gene therapies.

A small trial of an experimental vaccine has shown promising results for patients with the most aggressive type of breast ...

The study is the first to demonstrate that the nucleus relies on metabolic pathways to maintain the integrity and ... IMPDH2 relocates to the nucleus of TNBC cells to assist in DNA repair processes.